spiro-pyrano-pyrazole derivatives

螺-吡喃并-吡唑衍生物

Abstract

本发明涉及对于西格玛(σ)受体具有药物活性的式(I)的化合物,更具体而言,涉及一些螺-吡喃并-吡唑衍生物,制备这些化合物的方法,含有这些化合物的药物组合物,以及其在治疗法和预防法中的用途,特别是用于治疗精神病方面的用途。
The present invention relates to compounds of formula (I) having pharmacological activity towards the sigma (s) receptor, and more particularly to some spiro-pyrano-pyrazole derivatives, to processesof preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and prophylaxis, in particular for the treatment of psychosis.

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